Risk of Self-Reported Head Injury in the Development of Mild Cognitive
Impairment and Alzheimer's Disease
 
   Lead Investigator:    Christian LoBue
   Institution      :    UT Southwestern Medical Center
   E-Mail           :    christian.lobue@utsouthwestern.edu
   Proposal ID      :    406


   Publications:


1  Cullum M, Lobue C, Denney D, Hynan L, Rossetti H, Lacritz L, Hart J, Womack K
   Traumatic Brain Injury History and Age of Mild Cognitive Impairment Diagnosis
   Abstract  Alzheimers Dement,11(7):444,2015,

   PUBLISHED



2  LoBue C, Clem M, Wilmoth K, Lacritz L, Woon FL, Rossetti HC, Cullum CM
   Traumatic brain injury is associated with earlier age of diagnosis in mild cognitive impairment regardless of gender
   2015   Abstract  35th annual National Academy of Neuropsychology conference, Austin, TX , 

   ACCEPTED



3  LoBue C, Denney D, Hynan LS, Rossetti HC, Lacritz LH, Hart J, Womack KB, Woon FL, Cullum CM
   Self-Reported Traumatic Brain Injury and Mild Cognitive Impairment: Increased Risk and Earlier Age of Diagnosis
   Journal Article  J Alzheimers Dis,51:727-736,2016,PMC4853649

   PUBLISHED



4  LoBue C, Lacritz L, Hart J, Jr., Kyle W, Cullum M
   Self-Reported Head Injury and Earlier Age of Diagnosis of Mild Cognitive Impairment
   Abstract  Arch Clin Neuropsychol,29:512,2014,

   PUBLISHED



5  LoBue C, Lacritz LH, Rossetti HC, Hart J, Womack KB, Cullum CM
   Self-reported head injury and age of diagnosis in dementia
   2015   Abstract  43rd annual meeting of the International Neuropsychological Society, Denver, CO , 

   ACCEPTED



6  LoBue C, Wilmoth K, Cullum CM, Rossetti HC, Lacritz LH, Hynan LS, Hart J, Womack KB
   Traumatic brain injury history is associated with earlier age of onset of frontotemporal dementia
   Journal Article  J Neurol Neurosurg Psychiatry,87:817-820,2016,PMC4835269

   PUBLISHED





   Proposal Description:
   Traumatic brain injury (TBI) has shown to be a risk factor for the development    of Alzheimer's Disease (AD).   Mild cognitive impairment (MCI) is considered    a prodromal stage of AD however, the association between sustaining a head        injury and later development of mild cognitive impairment remains unknown.        This study aims to 1) determine the risk associated with a history of TBI and     later development of mild cognitive impairment and 2) assess if a history of      TBI increases the conversion rate from MCI to Alzheimer's Disease.